Job Description
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary Are you a MSc/PhD graduate within a chemistry discipline? Have you got the desire to join a company who play a part in improving health and lives? Do you have a passion for drug development? Charles River are looking for a Senior Scientist - Medicinal Chemistry to be based at our client site in Hatfield on an initial 12 month FTC . In this role, you will be working as part of a team of enthusiastic medicinal chemists designing and synthesising novel compounds with the goal being to identify a potential candidate suitable for drug development. What you'll be doing Plan and execute efficient synthetic routes to deliver final compounds to benefit your assigned project. Solve problems with synthetic routes and individual reactions or purifications to access target compounds aligned with project priorities. Follow local legislation and policies and procedures on safety and quality. Act with due care for the safety of yourself and others at all times. Present results, issues and plans around your own work at regular internal or external meetings for your project and client. Clearly communicate status of your own work, issues encountered and proposed solutions with your chemistry or project leader. Proficient in practical use of standard chemistry lab equipment to efficiently and safely complete reactions. Analyse reactions and isolated materials by LC/MS, NMR and other techniques as required to demonstrate structural identity and purity of intermediates and final compounds. Collaborate with chemistry colleagues to maintain a tidy and safe lab environment What we offer you A very comprehensive benefits package from day one, including a large pension contribution, private medical for you (and can add family members), private dental care, critical illness cover, bonus and more! Access to great discounts via our CREDS discount scheme. Global opportunities and strong career progression. The chance to work on several varied projects and liaise globally and nationally with other business areas. To be able make a difference to health and wellbeing of people. To continue your own career growth. Flexible and hybrid working. Parental leave. Group Life Assurance and Group Income Protection. Remote GP access 24/7. Well-being support and initiatives. Cycle to work scheme. Profile and Requirements • MSc/PhD in a relevant discipline (Synthetic Chemistry/Medicinal Chemistry/Organic Chemistry) • Previous exprience of working in a similar role within the CRO/Biotech/Pharma industry • Practical and theoretical knowledge of synthetic organic chemistry to enable efficient planning, execution and problem-solving of synthetic routes towards assigned target compounds, as well as routine purification and analysis of intermediates and final compounds. • To have good attention to detail, organisational and time management skills. • To have a dynamic, can-do attitude and a flexible approach to problem solving. • A desire to develop a career discovering new medicines for the future. • A commitment to personal development to enable future career progression. • A passion for practical synthetic chemistry. • Identify synthetic chemistry problems and work with colleagues to implement solutions. • To be able to interpret NMR and mass spectrometry data. • To be able to use scientific literature and provide solutions to technical problems. About Discovery Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market. About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021. At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.